Version  1.0
 File Size  713 kb
 File Count  1
 Create Date  July 13, 2022
 Update Date  July 13, 2022
 Telegram  Join Now



You have to wait 15 seconds.



Summary of Bioavailability and Bioequivalence

1. Bioavailability
Bioavailability could be a measurement of the extent of a therapeutically active medicine that reaches the systemic circulation and is therefore available at the location of action. For most medicines that are taken orally, the active ingredients are released within the gastrointestinal (GI) tract and gain their site of action via the circulation. Blood concentrations of the active ingredients and/or their active metabolites thereby provide a marker for the concentration at the positioning of action and a legitimate measure of bioavailability.

2. Bioequivalence
If two medicines are bioequivalent there's no clinically significant difference in their bioavailability. Although bioequivalence is most ordinarily discussed in relation to generic medicines, it's important to notice that bioequivalence studies also are performed for innovator medicines in some situations.