Toxic kinetics refers to the movement and fate, also named because the disposition, of
toxicants. The term is most typically used when describing the time course of absorption,
distribution, and elimination (including biotransformation and excretion) of toxicants in an
organism. Toxic kinetics is closely associated with pharmacokinetics, and will even be viewed
because the same discipline, with the sole difference being the category of compound
(toxicant or pharmaceutical) that's involved. Compared to typical pharmaceutical exposure,
exposure to toxicants is usually uncontrolled and variable, and really large doses is also
involved. Toxicants also are more likely to cause lesions and abnormal physiological function
which will alter the toxicant disposition, compared to exposures to pharmaceutical drugs
below toxic levels. When very large doses are involved, kinetic processes that may become
saturated are more likely to succeed in their maximum rates, leading to altered disposition.
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