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Syllabus of Unit 5 :-

1. Antidiabetic Agents
  • Insulin and its preparations
  • Sulfonyl ureas : Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride
  • Biguanides : Metformin
  • Thiazolidinediones : Pioglitazone, Rosiglitazone
  • Meglitinides : Repaglinide, Nateglinide
  • Glucosidase inhibitors : Acrabose, Voglibose
2. Local Anesthetics : SAR of Local anesthetics
3. Benzoic Acid derivatives : Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine.
4. Amino Benzoic acid derivatives : Benzocaine*, Butamben, Procaine*, Butacaine, Propoxycaine, Tetracaine, Benoxinate.
5. Lidocaine/Anilide derivatives : Lignocaine, Mepivacaine, Prilocaine, Etidocaine
6. Miscellaneous : Phenacaine, Diperodon, Dibucaine.*

1. Antidiabetic Agents

Antidiabetic drugs are medicines developed to stabilise and control glucose levels amongst people with diabetes. Antidiabetic drugs are commonly wont to manage diabetes.

There are variety of various styles of antidiabetic including:
  1. Insulin
  2. Pramlintide (Amylin)
  3. GLP-1 receptor agonists (such as Byetta and Victoza)
  4. Oral hypoglycemics (tablets)

2. Local Anesthetics

Local anaesthesia involves numbing a vicinity of the body employing a kind of medicine called an area anaesthetics.
These medicines is accustomed treat painful conditions, prevent pain during a procedure or operation, or relieve pain after surgery.

Unlike general anaesthetics, local anaesthetics don't cause you to lose consciousness.

This means they're generally safer, don't normally require any special preparation before they're used, and you'll get over them more quickly.

3. Sulfonyl Urea

Sulfonylureas are a gaggle of medicines wont to treat type 2 diabetes.

With type 2 diabetes, the body doesn't use the hormone insulin properly, resulting in elevated levels of glucose (glucose).

The first sulfonylureas were developed within the 1950s.

The drugs work by increasing the discharge of insulin from the pancreas.

Sulfonylureas are only 1 a part of a treatment plan for type 2 diabetes, which should also include diet and exercise to assist control glucose levels.