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Syllabus of Unit 1 :-

General Pharmacology
  1. Introduction to Pharmacology- Definition, historical landmarks and scope of pharmacology, nature and source of drugs, essential drugs concept and routes of drug administration, Agonists, antagonists (competitive and non competitive), spare receptors, addiction, tolerance, dependence, Tachyphylaxis, idiosyncrasy, allergy.

  2. Pharmacokinetics - Membrane transport, absorption, distribution, metabolism and excretion of drugs .Enzyme induction, enzyme inhibition, kinetics of elimination. 

What is Pharmacology ?

Pharmacology is that the study of the actions, mechanisms, uses and adverse effects of medication. A drug is any natural or synthetic substance that alters the state of a living organism.

Drugs are often divided into two groups :-
  1. Medicinal drugs : substances used for the prevention, treatment and diagnosis of disease.
  2. Nonmedicinal (social) drugs: substances used for recreational purposes. These drugs include illegal substances like cannabis, heroin and cocaine, as well as everyday substances like caffeine, nicotine and alcohol.
Although drugs may have a selective action, there's always a risk of adverse effects related to the employment of any drug, and the prescriber should assess the balance of desired and adverse effects when deciding which drug to prescribe.


What is Pharmacokinetics ?

Pharmacokinetics (PK) is that the study of how the body interacts with administered substances for the whole duration of exposure (medications for the sake of this article). this can be closely associated with but distinctly different from pharmacodynamics, which examines the drug’s effect on the body more closely. The four main parameters generally examined by this field include absorption, distribution, metabolism, and excretion (ADME). Wielding an understanding of those processes allows practitioners the flexibleness to prescribe and administer medications that may provide the best benefit at the bottom risk and permit them to form adjustments as necessary, given the numerous physiology and lifestyles of patients.