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Medicinal Chemistry II is the subject of B Pharmacy Semester 5 which is designed to impart the fundamental knowledge on the structure, chemistry and therapeutic value of drugs.

Previous Year Question Papers of Medicinal Chemistry II

The previous year question papers is uploaded by Carewell Pharmacy which is based on AKTU [ Dr. APJ Abdul Kalam Technical University ].

There is a Table of Content given below which help you to find out your required Year Question Paper. You can click on particular year which you want to redirect.

💡 Table of Content
  1. Prev. Yr Papers of Medicinal Chemistry II [ 2020 ]
  2. Prev. Yr Papers of Medicinal Chemistry II [ 2021 ]
  3. Prev. Yr Papers of Medicinal Chemistry II [ 2022 ]


Previous Year Question Papers of Medicinal Chemistry II [ 2020 ]    

SECTION A 
Ques.1 Ans all question in brief [ 10*2=20 ]
  1. Draw a structure and write uses of diphenhydramine hydrochloride.
  2. Write mechanism of action of methotrexate.
  3. Draw structure and write mechanism of action of verapamil.
  4. Draw the structure and uses of loop diuretics drugs.
  5. Discuss mechanism of action and uses of lovastatin.
  6. Write a short note on Digi toxin.
  7. Write mechanism of action and draw structure of sildenafil.
  8. Discuss the advantages of amide local anesthetics over ester local anesthetics. 
  9. Write a short note on thiazolidinedione.
  10. Discuss about metabolic pathway of insulin.

SECTION B 
Ques.2 Attempt any two question [ 2*10=20 ]
  1. Write the SAR and mechanism of action H2 receptor antagonists.
  2. Write the synthesis and MOA of Acetazolamide.
  3. Classify anti-anginal drug. Give the synthesis and SAR of isosorbide dinitrite.

SECTION C
Ques.3 Attempt any five question [ 5*7=35 ]
  1. Give the SAR and synthesis of disopyramide phosphate. 
  2. Classify anticoagulants. Write the SAR and synthesis of warfarin.
  3. Classify antithyroid drugs and write a detailed note on propylthiouracil.
  4. Classify sulphonyl uses and biguanides derivatives. Write a SAR of tolbutamide.
  5. Write the structural classification of local anesthetics. Write the mechanism of benzocaine.
  6. Write the SAR and mechanism of action of meclorethamine.
  7. Write the structural classification of oral contraceptives.


Previous Year Question Papers of Medicinal Chemistry II [ 2021 ]

SECTION A 
Ques.1 Ans all question in brief [ 10*2=20 ]
  1. Define Anti histaminic agents with suitable examples.
  2. Draw chemical structure of rabeprazole. 
  3. Write mechanism of action of antimetabolite.
  4. Define contransportor and symporter.
  5. Write the synthesis and uses of methyldopa.
  6. Classify Class I antiarrhythmic agent with example.
  7. Enlist the name of drug used in congestive heart failure.
  8. Draw chemical structure of Sildenafil and Tadalafil.
  9. Discuss the mechanism of action of Thiazolidinedione.
  10. Write the synthesis of Benzocaine and Procaine.
SECTION B 
Ques.2 Attempt any two question [ 2*10=20 ]
  1. Classify antihistaminic agents with their chemical structure. Explain SAR of antihistamines. Discuss the synthesis and uses of Cimetidine.
  2. What is hypertension. Discuss in detail about drugs acting on Renin-Angiotensin system.
  3. What are lipoproteins ? Classify Antihyperlipidemic agents with suitable examples. Discuss the SAR of fibric acid derivatives.
 
SECTION C
Ques.3 Attempt any five question [ 5*7=35 ]
  1. Describe the nomenclature and stereochemistry of steroids.
  2. Explain in detail about of local anaesthetics.
  3. Discuss SAR and mechanism of action of alkylating agents.
  4. Explain the synthesis and uses of acetazolamide, chlorthiazide and nitroglycerine.
  5. Write mechanism of action and uses of Menadione, Acetomenadione, Anisindione and clopidogrel. Also write the synthesis of warfarin.
  6. Write a note on Oral contraceptives. Discuss the mechanism of action and uses of Mifepristone, Norgestril and Levonorgestrol. 
  7. Discuss in detail about insulin and its preparation. Describe the mechanism of action, uses and synthesis of Tolbutamide.


Previous Year Question Papers of Medicinal Chemistry II [ 2022 ]

SECTION A 
Ques.1 Ans all question in brief [ 10*2=20 ]
  1. Draw any two structures of antimetabolites used as antineoplastic agents.
  2. Write synthesis of isosorbide dinitrite.
  3. What are oral contraceptives. Give examples.
  4. Discuss the mechanism of action and uses of acetazolamide.
  5. Give structure and mechanism of action of any one Antihyperlipidemic agent.
  6. Describe calcium channel blockers along with their uses.
  7. Discuss the role of digoxin in treatment of congestive heart failure.
  8. Define oral anticoagulants with examples.
  9. Give the synthesis of benzocaine.
  10. Write down the structure, mechanism of action and uses of rabeprazole.

SECTION B 
Ques.2 Attempt any two question [ 2*10=20 ]
  1. Classify diuretics. Explain SAR of thiazides diuretics along with the synthesis of chlorthiazide.
  2. Define and classify antihistaminic agents. Explain in detail about structures and uses of first generation H1 antihistaminic agents.
  3. What are antidiabetic agents ? Classify oral hypoglycemic agents and describe in detail about SAR and mechanism of action of sulfonylureas along with synthesis of tolbutamide.

SECTION C
Ques.3 Attempt any five parts of the question [ 5*7=35 ]
  1. Classify local anesthetics with examples and explain in detail about various benzoic acid derivatives.
  2. Describe antihypertensive drugs. Explain in detail about structures and mechanism of action of angiotensin converting enzyme inhibitors.
  3. Classify antineoplastic agents. Discuss in details about structure and mechanism of action of alkylating agents.
  4. Explain thyroid and antithyroid drug with structures and uses.
  5. Give classification of Antianginal drugs. Discuss in details structure, mechanism of action and uses of nitrates.
  6. Discuss in details about different corticosteroids. Give structures of cortisone and prednisolone.
  7. Classify antiarrhythmic drugs. Describe in detail about structures and mechanism of action of drugs belonging to class I.