Are you a student of M Pharm and worried about the M Pharm Notes ? If yes, then you are at the right blog post where you are going to find out your notes.

Specialization in M Pharm Includes :- 
  1. Pharmaceutics
  2. Industrial Pharmacy
  3. PH Chemistry
  4. PH Analysis
  5. PH Quality Assurance
  6. PH Regulatory Affairs
  7. PH Biotechnology
  8. Pharmacy Practice
  9. Pharmacology
  10. Pharmacognosy

M Pharm Notes

The M Pharm Notes pdf are upload as per the semester wise. By using the Table of Content, you can directly redirect to your required semester.

💡 Table of Content
  1. M Pharm Notes | Pharmaceutics
  2. M Pharm Notes | Industrial Pharmacy
  3. M Pharm Notes | PH Chemistry
  4. M Pharm Notes | PH Analysis
  5. M Pharm Notes | PH Quality Assurance
  6. M Pharm Notes | PH Regulatory Affairs
  7. M Pharm Notes | PH Biotechnology
  8. M Pharm Notes | Pharmacy Practice
  9. M Pharm Notes | Pharmacology
  10. M Pharm Notes | Pharmacognosy

1. M Pharm Notes | Pharmaceutics

This section is for those student whose doing in M. Pharm in Pharmaceutics. The subjects of Specialization in Pharmaceutics is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Pharmaceutics

Subjects (R22 Regulation, JNTUH)
Modern Pharmaceutics - I Click Here
Applied Biopharmaceutics &
Pharmacokinetics
Click Here
Advanced Physical Pharmaceutics Click Here
Drug Regulatory Affairs Click Here
Cosmetics and Cosmeceuticals Click Here
PH Validation Click Here
Research Methodology and IPR Click Here

Subjects (R21 Regulation, JNTUA)
Modern PH Analytical Techniques Click Here
Advanced Physical Pharmaceutics Click Here
Modern Pharmaceutics - I Click Here
Advanced Biopharmaceutics &
Pharmacokinetics
Click Here 

Subjects (PCI Syllabus)
Modern PH Analytical Techniques Click Here
Drug Delivery System Click Here
Modern Pharmaceutics Click Here
Regulatory Affair Click Here

Semester 2 | Pharmaceutics

Subjects (R21 Regulation, JNTUA)
Modern Pharmaceutics-II Click Here
Advanced Drug Delivery system Click Here
Nano Drug Delivery system Click Here
Industrial Pharmacy Click Here

Subjects (PCI Syllabus)
Molecular Pharmaceutics Click Here
Advanced Biopharmaceutics &
Pharmacokinetics
Click Here
Computer Aided Drug
Delivery System
Click Here
Cosmetic and Cosmeceuticals Click Here

Semester 3 | Pharmaceutics

Subject
Research Methodology and
Biostatistics
Click Here


Modern Pharmaceutical Analytical Technique M Pharm Notes

Modern Pharmaceutical Analytic Techniques Notes consists of following syllabus:-

Unit 1. a. UV-Visible spectroscopy: Introduction, Theory, Laws, Instrumentation associated with UV-Visible spectroscopy,
Choice of solvents and solvent effect and Applications of UV Visible spectroscopy.

Unit 1. b. IR spectroscopy: Theory, Modes of Molecular vibrations, Sample handling, Instrumentation of Dispersive and Fourier - Transform IR Spectrometer, Factors affecting vibrational frequencies and Applications of IR spectroscopy.

Unit 1.c. Spectroflourimetry: Theory of Fluorescence, Factors affecting fluorescence, Quenchers, Instrumentation and Applications of fluorescence spectrophotometer.

Unit 1.d. Flame emission spectroscopy and Atomic absorption spectroscopy: Principle, Instrumentation, Interferences and Applications.

Unit 2 - NMR Spectroscopy: Quantum numbers and their role in NMR, Principle, Instrumentation, Solvent requirement in NMR, Relaxation process, NMR signals in various compounds, Chemical shift, Factors influencing chemical shift, Spin-Spin coupling, Coupling constant, Nuclear magnetic double resonance.
Brief outline of principles of FT-NMR and 13C NMR. 
Applications of NMR spectroscopy.

Unit 3 - Mass Spectroscopy: Principle, Theory, Instrumentation of Mass Spectroscopy. 
Different types of ionization like electron impact, chemical, field, FAB and MALDI, APCI, ESI, APPI Analyzers of Quadrupole and Time of Flight, Mass fragmentation and its rules, Meta stable ions, Isotopic peaks and Applications of Mass spectroscopy.

Unit - 4 Chromatography: Principle, apparatus, instrumentation, chromatographic parameters, factors affecting resolution and applications of the following:
  1. Paper Chromatography
  2. Thin Layer Chromatography
  3. Ion Exchange Chromatography 
  4. Column Chromatography
  5. Gas Chromatography 
  6. High Performance Liquid Chromatography
  7. Affinity Chromatography
Unit 5 a. Electrophoresis: Principle, Instrumentation, Working conditions, factors affecting separation and applications of the following:
  1. Paper electrophoresis 
  2. Gel electrophoresis 
  3. Capillary electrophoresis 
  4. Zone electrophoresis 
  5. Moving boundary electrophoresis 
  6. Iso electric focusing
Unit 5.b. X ray Crystallography: Production of X rays, Different X-ray diffraction methods, Bragg‘s law, Rotating crystal technique, X ray powder technique, Types of crystals and applications of X-ray diffraction.

Unit 6 - Immunological assays : RIA (Radio immuno assay), ELISA, Bioluminescence assays.


Drug Delivery System M Pharm Notes

Drug Delivery System Notes consists of following syllabus:-

Unit 1. 
Sustained Release (SR) and Controlled Release (CR) formulations: Introduction & basic concepts, advantages/disadvantages, factors influencing, Physicochemical & biological approaches for SR/CR formulation, Mechanism of Drug Delivery from SR/CR formulation. 
Polymers: introduction, definition, classification, properties and application.
Dosage Forms for Personalized Medicine: Introduction, Definition, Pharmacogenetics. 
Categories of Patients for Personalized Medicines: Customized drug delivery systems, Bioelectronics Medicines, 3D printing of pharmaceuticals, Tele pharmacy.

Unit 2
Rate Controlled Drug Delivery Systems: Principles & Fundamentals, Types, Activation. 
Modulated Drug Delivery Systems : Mechanically activated, pH activated, Enzyme activated, and Osmotic activated Drug Delivery Systems 
Feedback regulated Drug Delivery Systems : Principles & Fundamentals.

Unit 3
Gastro-Retentive Drug Delivery Systems: Principle, concepts advantages and disadvantages. 
Modulation of GI transit time approaches to extend GI transit. 
Buccal Drug Delivery Systems: Principle of muco adhesion, advantages and
disadvantages, Mechanism of drug permeation, Methods of formulation and its evaluations.

Unit 4 - Occular Drug Delivery Systems: Barriers of drug permeation, Methods to overcome barriers.

Unit 5 - Transdermal Drug Delivery Systems: Structure of skin and barriers, Penetration enhancers, Transdermal Drug Delivery Systems, Formulation and evaluation.

Unit 6 - Protein and Peptide Delivery: Barriers for protein delivery.
Formulation and Evaluation of delivery systems of proteins and other macromolecules.

Unit 7 - Vaccine delivery systems: Vaccines, uptake of antigens, single shot vaccines, mucosal and transdermal delivery of vaccines.


Modern Pharmaceutics M Pharm Notes

Modern Pharmaceutics Notes consists of following syllabus:-

Unit 1.a. 
Preformation Concepts - Drug Excipient interactions different methods, kinetics of stability, Stability testing. 
Theories of dispersion and pharmaceutical Dispersion (Emulsion and Suspension, SMEDDS) preparation and stability 
Large and small volume parental - physiological and formulation consideration,
Manufacturing and evaluation.

Unit 1.b. Optimization techniques in Pharmaceutical Formulation: Concept and parameters of optimization, Optimization techniques in pharmaceutical formulation and processing. Statistical design, Response surface method, Contour designs, Factorial designs and application in formulation.

Unit 2
Validation : Introduction to Pharmaceutical Validation, Scope & merits of Validation, Validation and calibration of Master plan. 
ICH & WHO guidelines for calibration and validation of equipments, Validation of specific dosage form, Types of validation. 
Government regulation, Manufacturing Process Model, URS, DQ, IQ, OQ & P.Q. of facilities.

Unit 3
cGMP & Industrial Management: Objectives and policies of current good manufacturing practices, layout of buildings, services, equipments and their maintenance.
Production management: Production organization, , materials management, handling and transportation, inventory management and control, production and planning control, Sales forecasting, budget and cost control, industrial and personal relationship. 
Concept of Total Quality Management.

Unit 4 - Compression and Compaction: Physics of tablet compression, compression, consolidation, effect of friction, distribution of forces, compaction profiles. Solubility.

Unit 5 - Study of consolidation parameters: Diffusion parameters, Dissolution parameters and Pharmacokinetic parameters, Heckel plots, Similarity factors - f2 and f1, Higuchi and Peppas plot, Linearity Concept of significance, Standard deviation , Chi square
test, students T-test , ANOVA test.


Regulatory Affairs M Pharm Notes

Regulatory Affairs Notes consists of following syllabus:-

Unit 1.a. 
Documentation in Pharmaceutical industry: Master formula record, DMF (Drug Master File), distribution records.
Generic drugs product development Introduction , Hatch-Waxman act and amendments, CFR (CODE OF FEDERAL REGULATION) ,drug product performance, in-vitro, ANDA regulatory approval process, NDA approval process, BE and drug product assessment, in –vivo, scale up process approval changes, post marketing surveillance, outsourcing BA and BE to CRO.

Unit 1.b. Regulatory requirement for product approval: API, biologics, novel, therapies obtaining NDA, ANDA for generic drugs ways and means of US registration for foreign drugs.

Unit 2 
CMC, post approval regulatory affairs. Regulation for combination products and medical devices.
CTD and ECTD format, industry and FDA liaison. 
ICH - Guidelines of ICH-QSEM. 
Regulatory requirements of EU, MHRA, TGA and ROW countries.

Unit 3 - Non clinical drug development: Global submission of IND, NDA, ANDA. Investigation of medicinal products dossier, dossier (IMPD) and investigator brochure (IB).

Unit 4
Clinical trials: Developing clinical trial protocols. Institutional review board/ independent ethics committee Formulation and working procedures informed Consent process and procedures.
HIPAA - new, requirement to clinical study process,
pharmacovigilance safety monitoring in clinical trials.


Molecular Pharmaceutics M Pharm Notes

Molecular Pharmaceutics Notes consists of following syllabus:-

Unit 1. Targeted Drug Delivery Systems: Concepts, Events and biological process involved in drug targeting. Tumor targeting and Brain specific delivery.

Unit 2
Targeting Methods: Introduction, preparation and evaluation.
Nano Particles & Liposomes: Types, preparation and evaluation.

Unit 3 
Micro Capsules / Micro Spheres: Types, preparation and evaluation.
Monoclonal Antibodies: preparation and application, preparation and application of Niosomes, Aquasomes, Phytosomes, Electrosomes.

Unit 4 
Pulmonary Drug Delivery Systems : Aerosols, propellants, Containers Types, preparation and evaluation, Intra Nasal Route
Delivery systems: Types, preparation and evaluation. 

Unit 5
Nucleic acid based therapeutic delivery system : Gene therapy, introduction (ex-vivo & in-vivo gene therapy). Potential target diseases for gene therapy (inherited disorder and cancer). 
Gene expression systems (viral and nonviral gene transfer)
Liposomal gene delivery systems.
Bio distribution and Pharmacokinetics, knowledge of therapeutic
antisense molecules and aptamers as drugs of future.


Advanced Biopharmaceutics and Pharmacokinetics M Pharm Notes

Advanced Biopharmaceutics and Pharmacokinetics Notes consists of following syllabus:-

Unit 1. 
Drug Absorption from the Gastrointestinal Tract: Gastrointestinal tract, Mechanism of drug absorption, Factors affecting drug absorption, pH–partition theory of drug absorption.
Formulation and physicochemical factors: Dissolution rate, Dissolution process, Noyes–Whitney equation and drug dissolution, Factors affecting the dissolution rate. 
Gastrointestinal absorption: Role of the dosage form: Solution (elixir, syrup and solution) as a dosage form ,Suspension as a dosage form, Capsule as a dosage form, Tablet as a dosage form ,Dissolution methods ,Formulation and processing factors, Correlation of in vivo data with in vitro dissolution data.
Transport model: Permeability-Solubility-Charge State and the pH Partition. Hypothesis, Properties of the Gastrointestinal Tract (GIT), pH, Microclimate Intracellular pH Environment, Tight-Junction
Complex.

Unit 2
Biopharmaceutics considerations in drug product design and In Vitro Drug Product Performance: Introduction, biopharmaceutics factors affecting drug bioavailability, rate-limiting steps in drug absorption, physicochemical nature of the drug formulation
Factors affecting drug product performance, in vitro: Dissolution and drug release testing, compendia methods of dissolution, alternative methods of dissolution testing, meeting dissolution requirements, problems of variable control in dissolution testing performance of drug products. 
In vitro–in vivo correlation, dissolution profile comparisons, drug product stability, considerations in the design of a drug product.

Unit 3 
Pharmacokinetics: Basic considerations, pharmacokinetic models.
Compartment modeling: one compartment model- IV bolus, IV infusion, extra-vascular. 
Multi compartment model: Two compartment - model in brief. 
Non-linear pharmacokinetics: cause of non-linearity, Michaelis – Menten equation, estimation of kmax and vmax. 
Drug interactions: introduction, the effect of protein binding interactions, the effect of tissue-binding
interactions, cytochrome p450-based drug interactions, drug interactions linked to transporters.

Unit 4
Drug Product Performance, In Vivo: Bioavailability and Bioequivalence: drug product performance, purpose of bioavailability studies, relative and absolute availability. 
Methods for assessing bioavailability, bioequivalence studies, design and evaluation of bioequivalence studies, study designs, crossover study designs, evaluation of the data, bioequivalence example, study submission and drug review process. biopharmaceutics classification system, methods. Permeability: In-vitro, in-situ and In-vivo methods. generic biologics (biosimilar drug products),clinical significance of bioequivalence studies, special concerns in bioavailability and bioequivalence studies, generic substitution.

Unit 5
Application of Pharmacokinetics: Modified-Release Drug Products, Targeted Drug Delivery Systems and Biotechnological Products. 
Introduction to Pharmacokinetics and pharmacodynamics, drug interactions. Pharmacokinetics and
pharmacodynamics of biotechnology drugs. Introduction, Proteins and peptides, Monoclonal antibodies, Oligonucleotides, Vaccines (immunotherapy), Gene therapies.


Computer Aided Drug Development M Pharm Notes

Computer Aided Drug Development Notes consists of following syllabus:-

Unit 1.a. 
Computers in Pharmaceutical Research and Development: A General Overview: History of Computers in Pharmaceutical Research and Development. 
Statistical modeling in Pharmaceutical research and development: Descriptive versus Mechanistic Modeling, Statistical Parameters, Estimation, Confidence Regions, Nonlinearity at the Optimum, Sensitivity Analysis, Optimal Design, Population Modeling.

Unit 1.b. 
Quality-by-Design In Pharmaceutical Development: Introduction, ICH Q8 guideline, Regulatory and industry views on QbD, Scientifically based QbD - examples of application.

Unit 2 
Computational Modeling Of Drug Disposition: Introduction, Modeling Techniques: Drug Absorption, Solubility, Intestinal Permeation, Drug Distribution, Drug Excretion, Active Transport;
P-gp, BCRP, Nucleoside Transporters, hPEPT1, ASBT, OCT, OATP, BBB-Choline Transporter.

Unit 3 
Computer-aided formulation development: Concept of optimization, Optimization parameters,
Factorial design, Optimization technology & Screening design. 
Computers in Pharmaceutical Formulation: Development of pharmaceutical emulsions, micro emulsion drug carriers 
Legal Protection of Innovative Uses of Computers in R&D, The Ethics of Computing
in Pharmaceutical Research, Computers in Market analysis.

Unit 4 a. 
Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation. Introduction, Theoretical background, Model construction, Parameter sensitivity analysis,
Virtual trial, Fed vs. fasted state, In vitro dissolution and in vitroin vivo correlation, Bio waiver considerations

Unit 4.b. Computer Simulations in Pharmacokinetics and Pharmacodynamics: Introduction, Computer Simulation: Whole Organism, Isolated Tissues, Organs, Cell, Proteins and Genes.

Unit 4.c. Computers in Clinical Development: Clinical Data Collection and Management, Regulation of Computer Systems.

Unit 5 Artificial Intelligence (AI), Robotics and Computational fluid dynamics: General overview, Pharmaceutical Automation, Pharmaceutical applications, Advantages and Disadvantages. Current Challenges and Future Directions.


Cosmetics and Cosmeceuticals M Pharm Notes

Cosmetics and Cosmeceuticals Notes consists of following syllabus:-

Unit 1 
Cosmetics - Regulatory : Definition of cosmetic products as per Indian regulation. Indian regulatory requirements for labeling of cosmetics.
Regulatory provisions relating to import of cosmetics, Misbranded and spurious cosmetics. 
Regulatory provisions relating to manufacture of cosmetics - Conditions for obtaining license, prohibition of manufacture and sale of certain cosmetics, loan license, offences and penalties.

Unit 2 
Cosmetics - Biological aspects : Structure of skin relating to problems like dry skin, acne, pigmentation, prickly heat, wrinkles and body odor.  Structure of hair and hair growth cycle. 
Common problems associated with oral cavity. Cleansing and care needs for face, eye lids, lips, hands, feet, nail, scalp, neck, body and under-arm.

Unit 3 
Formulation Building blocks: Building blocks for different product formulations of cosmetics/cosmeceuticals. 
Surfactants - Classification and application. 
Emollients, rheological additives: Classification and application. Antimicrobial used as preservatives, their merits and demerits. 
Factors affecting microbial preservative efficacy. Building blocks for formulation of a moisturizing cream, vanishing cream, cold cream, shampoo and toothpaste. Soaps and syndetbars.
Perfumes: Classification of perfumes. Perfume ingredients listed as allergens in EU regulation.
Controversial ingredients: Parabens, formaldehyde liberators, dioxane.

Unit 4
Design of cosmeceuticals products: Sun protection, sunscreens classification and regulatory aspects. Addressing dry skin, acne, sun-protection, pigmentation, prickly heat, wrinkles, body odor, dandruff, dental cavities, bleeding gums, mouth odor and sensitive teeth through cosmeceuticals formulations.

Unit 5
Herbal Cosmetics : Herbal ingredients used in Hair care, skin care and oral care. Review of guidelines for herbal cosmetics by private bodies like cosmos with respect to preservatives, emollients, foaming agents, emulsifiers and rheology modifiers. 
Challenges in formulating herbal cosmetics

2. M Pharm Notes | Industrial Pharmacy

This section is for those student whose doing in M. Pharm in Industrial Pharmacy. The subjects of Specialization in Industrial Pharmacy is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Industrial Pharmacy

Subjects
Modern PH Analytical Techniques Click Here
Pharmaceutical Formulation
Development
Click Here
Novel drug delivery systems Click Here
Intellectual Property Rights Click Here


Semester 2 | Industrial Pharmacy

Subjects
Advanced Biopharmaceutics and
Pharmacokinetics
Click Here
Scale up and Technology Transfer Click Here
Pharmaceutical Production Technology Click Here
Entrepreneurship Management Click Here


Semester 3 | Industrial Pharmacy

Subject
Research Methodology and
Biostatistics
Click Here


3. M Pharm Notes | PH Chemistry

This section is for those student whose doing in M. Pharm in PH Chemistry. The subjects of Specialization in PH Chemistry is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | PH Chemistry

Subjects
Modern PH Analytical Techniques Click Here
Advanced Organic Chemistry - Click Here
Advanced Medicinal Chemistry Click Here
Chemistry of Natural Products Click Here


Semester 2 | PH Chemistry

Subjects
Advanced Spectral Analysis Click Here
Advanced Organic Chemistry-II Click Here
Computer Aided Drug Design Click Here
Pharmaceutical Process Chemistry Click Here


Semester 3 | PH Chemistry

Subject
Research Methodology and
Biostatistics
Click Here


4. M Pharm Notes | PH Analysis

This section is for those student whose doing in M. Pharm in PH Analysis. The subjects of Specialization in PH Analysis is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | PH Analysis

Subjects (R22 Regulation, JNTUH)
Modern PH Analytical Techniques Click Here
PH Food Analysis Click Here
Drug regulatory Affairs Click Here
Drug regulatory Affairs Click Here
PH Validation Click Here
Cosmetics and Cosmeceuticals Click Here
Research Methodology & IPR Click Here

Subjects (PCI Syllabus)
Modern PH Analytical Techniques Click Here
Advanced Pharmaceutical Analysis Click Here
Pharmaceutical Validation Click Here
Food Analysis Click Here

Subjects (R21 Regulation, JNTUA)
Modern PH Analytical Techniques Click Here
Advanced Pharmaceutical Analysis Click Here
Pharmaceutical Food Analysis Click Here
Quality Control & Quality Assurance Click Here


Semester 2 | PH Analysis

Subjects (PCI Syllabus)
Advanced Instrumental Analysis Click Here
Modern Bio-Analytical Techniques Click Here
Quality Control and Quality Assurance Click Here
Herbal and Cosmetic Analysis Click Here

Subjects (R21 Regulation, JNTUA)
Advanced Instrumental Analysis Click Here
Modern Bio-Analytical Techniques Click Here
Pharmaceutical Validation Click Here
Herbal and Cosmetic Analysis Click Here


Semester 3 | PH Analysis

Subject
Research Methodology and
Biostatistics
Click Here


5. M Pharm Notes | PH Quality Assurance

This section is for those student whose doing in M. Pharm in PH Quality Assurance. The subjects of Specialization in PH Quality Assurance is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | PH Quality Assurance

Subjects
Modern PH Analytical Techniques Click Here
Quality Management System Click Here
Quality Control and Quality
Assurance
Click Here
Product Development and
Technology Transfer
Click Here


Semester 2 | PH Quality Assurance

Subjects
Hazards and Safety Management Click Here
Pharmaceutical Validation Click Here
Audits and Regulatory Compliance Click Here
Pharmaceutical Manufacturing
Technology
Click Here


Semester 3 | PH Quality Assurance

Subject
Research Methodology and
Biostatistics
Click Here


6. M Pharm Notes | Regulatory Affairs

This section is for those student whose doing in M. Pharm in Regulatory Affairs. The subjects of Specialization in Regulatory Affairs is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Regulatory Affairs

Subjects
Good Regulatory Practices Click Here
Documentation and Regulatory Writing Click Here
Clinical Research Regulations Click Here
Regulations and Legislation Click Here


Semester 2 | Regulatory Affairs

Subjects
Regulatory Aspects of Drugs &
Cosmetics
Click Here
Regulatory Aspects of Herbal &
Biologicals
Click Here
Regulatory Aspects of Medical
Devices
Click Here
Regulatory Aspects of Food &
Nutraceuticals
Click Here


Semester 3 | Regulatory Affairs

Subject
Research Methodology and
Biostatistics
Click Here


7. M Pharm Notes | PH Biotechnology

This section is for those student whose doing in M. Pharm in PH Biotechnology. The subjects of Specialization in PH biotechnology is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | PH Biotechnology

Subjects
Modern PH Analytical Techniques Click Here
Microbial And Cellular Biology Click Here
Bioprocess Eng and Technology Click Here
Advanced PH Biotechnology Click Here


Semester 2 | PH Biotechnology

Subjects
Proteins and protein Formulation Click Here
Immunotechnology Click Here
Bioinformatics and Computer
Technology
Click Here
Biological Evaluation of Drug
Therapy
Click Here


Semester 3 | PH Biotechnology

Subject
Research Methodology and
Biostatistics
Click Here


8. M Pharm Notes | Pharmacy Practice

This section is for those student whose doing in M. Pharm in Pharmacy Practice. The subjects of Specialization in Pharmacy Practice is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Pharmacy Practice

Subjects
Clinical Pharmacy Practice Click Here
Hospital & Community
Pharmacy
Click Here
Clinical Research Click Here
Pharmacotherapeutics-I Click Here


Semester 2 | Pharmacy Practice

Subjects
Principles of Quality Use of
Medicines
Click Here
Pharmacotherapeutics II Click Here
Clinical Pharmacokinetics and
Therapeutic Drug Monitoring
Click Here
Pharmacoepidemiology &
Pharmacoeconomics
Click Here


Semester 3 | Pharmacy Practice

Subject
Research Methodology and
Biostatistics
Click Here


9. M Pharm Notes | Pharmacology

This section is for those student whose doing in M. Pharm in Pharmacology. The subjects of Specialization in Pharmacology is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Pharmacology

Subjects (R22 Regulation, JNTUA)
Advanced Pharmacology - I Click Here
Clinical Pharmacology &
Pharmacotherapeutics
Click Here
Clinical Research &
Pharmacovigilance
Click Here
Research Methodology and IPR Click Here

Subjects (PCI Syllabus)
Modern PH Analytical Techniques Click Here
Advanced Pharmacology-I Click Here
Pharmacological and Toxicological
Screening Methods-I
Click Here
Cellular and Molecular Pharmacology Click Here

Subjects (R21 Regulation, JNTUA)
Modern PH Analytical Techniques Click Here
Advanced Pharmacology-I Click Here
Clinical Pharmacology and
Pharmacotherapeutics
Click Here
Cellular and Molecular Pharmacology Click Here


Semester 2 | Pharmacology

Subjects (PCI Syllabus)
Advanced Pharmacology II Click Here
Pharmacological and Toxicological
Screening Methods-II
Click Here
Principles of Drug Discovery Click Here

Subjects (R21 Regulation, JNTUA)
Advanced Pharmacology- II Click Here
Pharmacological Screening Methods
& Toxicology
Click Here
Principles of Drug Discovery Click Here
Clinical research and
Pharmacovigilance
Click Here


Semester 3 | Pharmacology

Subject
Research Methodology and
Biostatistics
Click Here


Advanced Pharmacology I M Pharm Notes

Advanced Pharmacology I Notes consists of the following syllabus:-

Unit 1. General Pharmacology
a. Pharmacokinetics: The dynamics of drug absorption, distribution, biotransformation and elimination. Concepts of linear and non-linear compartment models. Significance of Protein
binding.
b. Pharmacodynamics: Mechanism of drug action and the relationship between drug concentration and effect. Receptors, structural and functional families of receptors, quantitation of drug
receptors interaction and elicited effects.

Unit 2. Neurotransmission
a. General aspects and steps involved in neurotransmission.
b. Neurohumoral transmission in autonomic nervous system (Detailed study about neurotransmitters- Adrenaline and Acetylcholine).
c. Neurohumoral transmission in central nervous system (Detailed study about neurotransmitters- histamine, serotonin, dopamine, GABA, glutamate and glycine].
d. Non adrenergic non cholinergic transmission (NANC). Cotransmission.

Systemic Pharmacology
A detailed study on pathophysiology of diseases, mechanism of action, pharmacology and toxicology of existing as well as novel drugs used in the following systems.
Autonomic Pharmacology
Parasympathomimetics and lytics, sympathomimetic and lytics, agents affecting neuromuscular junction

Unit 3. Central nervous system Pharmacology
General and local anesthetics
Sedatives and hypnotics, drugs used to treat anxiety.
Depression, psychosis, mania, epilepsy, neurodegenerative diseases.
Narcotic and non-narcotic analgesics.

Unit 4. Cardiovascular Pharmacology
Diuretics, antihypertensives, antiischemics, anti- arrhythmics, drugs for heart failure and hyperlipidemia. 
Hematinics, coagulants , anticoagulants, fibrinolytics and antiplatelet drugs.

Unit 5. Autocoid Pharmacology
The physiological and pathological role of Histamine, Serotonin, Kinins Prostaglandins Opioid autocoids.
Pharmacology of antihistamines, 5HT antagonists.


Pharmacological and Toxicological Screening Method I M Pharm Notes

Pharmacological and Toxicological Screening Method I Notes Consists of following syllabus:-

Unit 1. Laboratory Animals
Common laboratory animals: Description, handling and applications of different species and strains of animals.
Transgenic animals: Production, maintenance and applications
Anaesthesia and euthanasia of experimental animals.
Maintenance and breeding of laboratory animals.
CPCSEA guidelines to conduct experiments on animals

Good laboratory practice.
Bioassay - Principle, scope and limitations and methods

Unit 2
Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models.
General principles of preclinical screening. 
CNS Pharmacology: behavioral and muscle co ordination, CNS stimulants and depressants, anxiolytics, anti-psychotics, anti epileptics and nootropics. 
Drugs for neurodegenerative diseases like Parkinsonism, Alzheimers and multiple sclerosis. Drugs acting on Autonomic Nervous System.

Unit 3
Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models.
Respiratory Pharmacology: anti-asthmatics, drugs for COPD and anti allergics. 
Reproductive Pharmacology: Aphrodisiacs and antifertility agents Analgesics, antiinflammatory and antipyretic agents. 
Gastrointestinal drugs: anti ulcer, anti -emetic, antidiarrheal and laxatives.

Unit 4
Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models.
Cardiovascular Pharmacology: antihypertensives, antiarrythmics, antianginal, antiatherosclerotic agents and diuretics. 
Drugs for metabolic disorders like anti-diabetic, antidyslipidemic agents.
Anti cancer agents. Hepatoprotective screening methods.

Unit 5 
Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models.
Iimmunomodulators, Immunosuppressants and immunostimulants

General principles of immunoassay: theoretical basis and optimization of immunoassay, heterogeneous and homogenous immunoassay systems. 
Immunoassay methods evaluation; protocol outline, objectives and preparation. 
Immunoassay for digoxin and insulin.
Limitations of animal experimentation and alternate animal experiments.
Extrapolation of in vitro data to preclinical and preclinical to humans.


Cellular and Molecular Pharmacology M Pharm Notes

Cellular and Molecular Pharmacology Notes consists of the following syllabus:-

Unit 1. Cell biology
Structure and functions of cell and its organelles
Genome organization: Gene expression and its regulation, importance of siRNA and micro RNA, gene mapping and gene sequencing
Cell cycles and its regulation.
Cell death - events, regulators, intrinsic and extrinsic pathways of apoptosis.
Necrosis and autophagy.

Unit 2. Cell signaling
Intercellular and intracellular signaling pathways.
Classification of receptor family and molecular structure ligand gated ion channels; G-protein coupled receptors, tyrosine kinase receptors and nuclear receptors.
Secondary messengers: cyclic AMP, cyclic GMP, calcium ion, inositol 1,4,5-trisphosphate, (IP3), NO, and diacylglycerol.
Detailed study of following intracellular signaling pathways: cyclic AMP signaling pathway, mitogen-activated protein kinase (MAPK) signaling, Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway.

Unit 3 
Principles and applications of genomic and proteomic tools DNA electrophoresis, PCR (reverse transcription and real time), Gene sequencing, micro array technique, SDS page, ELISA and
western blotting,
Recombinant DNA technology and gene therapy
Basic principles of recombinant DNA technology- Restriction enzymes, various types of vectors. Applications of recombinant, DNA technology.
Gene therapy- Various types of gene transfer techniques, clinical applications and recent advances in gene therapy.

Unit 4 Pharmacogenomics
Gene mapping and cloning of disease gene.
Genetic variation and its role in health/ pharmacology.
Polymorphisms affecting drug metabolism.
Genetic variation in drug transporters.
Genetic variation in G protein coupled receptors.
Applications of proteomics science: Genomics, proteomics, metabolomics, functionomics, nutrigenomics.
Immunotherapeutics, Types of immunotherapeutics, humanisation antibody therapy.
Immunotherapeutics in clinical practice.

Unit 5 a. Cell culture techniques
Basic equipments used in cell culture lab. Cell culture media, various types of cell culture, general procedure for cell cultures; isolation of cells, subculture, cryopreservation, characterization of
cells and their application.
Principles and applications of cell viability assays, glucose uptake assay, Calcium influx assays
Principles and applications of flow cytometry
b. Biosimilars

10. M Pharm Notes | Pharmacognosy

This section is for those student whose doing in M. Pharm in Pharmacognosy. The subjects of Specialization in Pharmacognosy is further divided into 4 Semester.
Kindly check out your semester and subjects from the below tables :-

Semester 1 | Pharmacognosy

Subjects
Modern PH Analytical Techniques Click Here
Advanced Pharmacognosy-1 Click Here
Phytochemistry Click Here
Industrial Pharmacognostical Technology Click Here


Semester 2 | Pharmacognosy

Subjects
Medicinal Plant biotechnology Click Here
Advanced Pharmacognosy-II Click Here
Indian system of medicine Click Here
Herbal cosmetics Click Here


Semester 3 | Pharmacognosy

Subject
Research Methodology and
Biostatistics
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