Physical Pharmaceutics I is the subject of B. Pharmacy IIIrd Semester. In this blog, Physical Pharmaceutics I Important Questions is provided which will help the students to do better in their examination and score the better marks. 

Physical pharmaceutics is the branch of pharmacy that concentrates on the applications of physics and chemistry to the study of pharmacy. In other words, it is the study of the effects that dosage forms have on their environment by addressing issues at the molecular level. 

Physical Pharmaceutics I Important Questions

There is a Table of Content given below which help you to find out your required Unit Important Question. You can click on particular unit which you want to redirect.

💡 Table of Content

Physical Pharmaceutics I Important Questions [ Unit 1 ]

Ques.1 Enumerate and Elaborate factor affecting solubility.
Ques.2 Define Solubility. Discuss solubility of liquid in liquids. [OR] Discuss solubility of solid in liquid of gas in liquids.
Ques.3 Discuss mechanism of Solute-Solvent interaction.
Ques.4 Discuss in details about Raoult's Law [Ideal & Non-Ideal] and its application.
Ques.5 Discuss in details about distribution law and its application and limitation.
Ques.6 Write diffusion principle in biological system.

Physical Pharmaceutics I Important Questions [ Unit 2 ]

Ques.1 Discuss physiochemical properties of drugs in details.
Ques.2 What are the various states of matter and how can the various states of matter be changed.
Ques.3 Describe sublimation critical point and eutectic mixture.
Ques.4 Describe determination and application of dielectric constants and dissociation constant.
Ques.5 Difference between crystalline and amorphous solid.
Ques.6 Write short note on :- 
  • Dipole moment
  • Latent Heat
  • Vapour Pressure
  • Relative Humidity
  • Aerosol-Inhalers
  • Polymorphism

Physical Pharmaceutics I Important Questions [ Unit 3 ]

Ques.1 Elaborate method for measuring surface and interfacial tension.
Ques.2 What is interfacial tension and their method of measurement.
Ques.3 What is spreading coefficient.
Ques.4 Explain solubilization and detergency.
Ques.5 What is Surface Active Agents (surfactants) and HLB Scale.
Ques.6 What is Surface Free Energy.
Ques.7 What is adsorption. Discuss in details.

Physical Pharmaceutics I Important Questions [ Unit 4 ]

Ques.1 Describe and discuss classification of complexes. [OR] Classify Complexes. Discuss metal ion complexes in details.
Ques.2 Discuss in details about protein binding.
Ques.3 Write method of analysis of complex formation.
Ques.4 Discuss thermodynamics treatment of stability constant.
Ques.5 Define Ligands and its types.
Ques.6 How the bonding of drugs to protein influence their action.

Physical Pharmaceutics I Important Questions [ Unit 5 ]

Ques.1 Discuss different method of adjusting tonicity and pH.
Ques.2 Write different method for determination of pH.
Ques.3 Discuss in detail about Sorensen's pH scale.
Ques.4 Define Buffers. Buffers in pharmaceutical and biological system.
Ques.5 Discuss Buffer Equation in details [Hesselbatch Equation] 
Ques.6 Write a note on :- 
  • Buffer Capacity
  • Buffer Isotonic Solution
  • Buffer on Buffer Solution

Ques.7 Define buffer and its classification and write about buffer action.
Ques.8 Define buffer isotonic solution and their method od adjusting tonicity.

Physical Pharmaceutics I Important Questions [ Very Short ]

Ques.1 Define Salvation.
Ques.2 Define Association.
Ques.3 Difference between crystalline and amorphous solids.
Ques.4 Define Solubility with example.
Ques.5 Define saturated solutions.
Ques.6 Discuss critical solution temperature and application.
Ques.7 Define Ideal Solution Parameters.
Ques.8 What is binary solutions.
Ques.9 What is solubility expression and write condition for sparingly soluble.
Ques.10 What is Real Solution ?
Ques.11 Define Dipole Moment.
Ques.12 Define Liquid Complexes and liquid crystals.
Ques.13 What do you understand by glassy states.
Ques.14 Write brief note on Polymerization. 
Ques.15 Define optical rotation or optical activity.
Ques.16 Define Surface Tension.
Ques.17 Define liquid interface.
Ques.18 What is surface free energy.
Ques.19 What is HLB Scale.
Ques.20 Define interfacial tension.
Ques.21 Define Complexation.
Ques.22 Define Protein Binding.
Ques.23 Define Ligands.
Ques.24 What is coordinate complex.
Ques.25 Define Clatharates.
Ques.26 Define Buffer Equation.
Ques.27 Define Buffer capacity.
Ques.28 Define Sorensen's pH scale.
Ques.29 Write equation for basic buffer (weak base and its salts)
Ques.30 Discuss Buffer Isotonic Solution.
Ques.31 Classify Surfactants.
Ques.32 Define Raoult's Law.
Ques.33 What are Eutectic Mixtures.
Ques.34 Denote buffer equation for a weak acid and its salts.
Ques.35 Enlist limitation of distribution law.
Ques.36 Define Diffusion.
Ques.37 What is Henry's law.
Ques.38 What is Charle's Law.
Ques.39 What is short note on partially miscible liquid.
Ques.40 What is crystalline structures of complexes.