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Physical Pharmaceutics II is the subject of B. Pharmacy Semester 4 which deals with the varied physical and physiochemical properties and principle involved in dosage forms/formulations. Theory and practical component of the subject help the student to induce a much better insight into various areas of formulation research, development and stability studies of pharmaceutical dosage forms.

The previous year ques. papers is uploaded by Carewell Pharmacy which is based on RUHS [ Rajasthan University of Health Science ].

Previous Year Question Papers of Physical Pharmaceutics II

There is a Table of Content given below which help you to find out your required Year Question Paper. You can click on particular year which you want to redirect.

💡 Table of Content

Previous Year Ques. Papers of Physical Pharmaceutics II [ 2020 ]

Ques.1 Answer the following in very short [ 5*2=10 ]
  1. Define Shell Life. What additional information should be specified along with shelf life on the label of the product.
  2. Describe the application of HLB system in the preparation of Emulsion.
  3. What are the advantages and disadvantages of microscopy method of study of powders.
  4. What are the structured vehicles ? What kind of properties they should possesses.
  5. Give the application of order of reaction,

Ques.2 Answer the following in very short [ 5*2=10 ]
  1. Define Newtonian Flow. Give two example.
  2. Describe two methods for identifying the type of emulsion.
  3. What is the difference between retest period and expiry period.
  4. Write identification test for emulsion.
  5. What is plastic and elastic deformation ?

Answer (any two) of following in Long Answer [ 2*10=20 ]
Ques.3 Explain the oxidative decomposition of pharmaceutical preparation with suitable examples. Mention the measure to prevent oxidative decompositions.
Ques.4 Classify and define different order of reaction with the equation. Add a note on method to determine order of reaction.
Ques.5 Define thixotrophy. Draw different types of thixotropic curves and explain the mechanism for their behavior with suitable examples.

Ques.6 Answer (any four) of following in short answer [ 4*5=20 ] 
  1. Explain the objectives and scope of ICH guild lines of stability testing.
  2. Draw the flow curve for anti-thixotropic flow and explain its mechanism.
  3. Describe the mechanism of action of co-solvent and surfactants in the dispersion of solids in water.
  4. Explain DLVO theory with energy curves. How this is applied in stabilizing the colloidal dispersion.
  5. Describe an accelerated method for the evaluation of physical stability of an emulsion.

Ques.7 Answer (any three) of following in short answer [ 3*5=15 ]
  1.  Describe Andreasen pipette method of analyzing the particle size.
  2. Distinguish plastic and pseudo plastic flow with suitable examples.
  3. Define controlled flocculation.
  4. What are association colloids ? Mention the mechanism of formation of micelles with one suitable example.

Previous Year Ques. Papers of Physical Pharmaceutics II [ 2021 ]

Ques.1 Answer the following in very short [ 5*2=10 ]
  1. Explain the term "Colloid". Mention one example for the same.
  2. How is thixotropic related to pseudo plastic flow ? Explain Brownian movement. Which formulation exhibit this movement.
  3. Highlight the role of polymers in the formulation of suspension.
  4. List different thickening agents that are used in o/w and w/o types of emulsion.
  5. Explain the term QSEM as per ICH guidelines.

Ques.2 Answer the following in very short [ 5*2=10 ]
  1. Describe the selection of a viscometer for studying the rheology of fluids.
  2. List different characteristic of a good emulsion.
  3. Write the Michaelis-Menton equation and explain its importance.
  4. Explain the term Q10 and its application.
  5. Define angle of repose. Suggest two methods to improve the flow properties of granules.

Answer (any two) of following in Long Answer [ 2*10=20 ]
Ques.3 Discuss the various method of particle size determination and its application.
Ques.4 Discuss in details about theories of emulsification.
Ques.5 Describe the flow behavior of Newtonian and non-Newtonian system, giving suitable examples.

Ques.6 Answer (any four) of the following in short answer [ 4*5=20 ]
  1. What is the principle of coulter counter ?
  2. Give the pharmaceutical application of Colloids.
  3. What are the desired properties of an ideal suspension ?
  4. What are the limitation of capillary viscometer.
  5. Discuss the effect of light, temperature and pH on the rate of decomposition of drug.

Ques.7 Answer (any three) of the following in short answer [ 3*5=15 ]
  1. Write a note on derived properties of powders.
  2. Write a note on Heckle Equation.
  3. Discuss the various factors influencing the chemical and physical degradation of pharmaceutical products.
  4. Define three types of particles diameters. Mention the methods for determining them.