You are reading this blog then you must be a student of B. Pharmacy [ Bachelor of Pharmacy ] and searching for the previous year question papers of Medicinal Chemistry I.

If you are reading this blog, then I can say with confidence that you are also facing the trouble or getting confuse for the upcoming examination of Medicinal Chemistry I. I know that the examination is little bit hard but after practicing the previous years question paper, you get some confidence to attempt the examination which results in scored the good marks.

As you are reading at Carewell Pharmacy then you will get a sure shot solution for this Medicinal Chemistry I Examination by checking the previous years question paper.

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Medicinal chemistry I is the subject of B Pharmacy Semester 4 which focuses on the molecular aspects of drug action : interactions with the drug targets from both the drug and therefore the target point of view, the link of drug chemical structure to drug action and also the effects of metabolism on the drug structure and hence its action.

The previous year question papers is uploaded by Carewell Pharmacy which is based on RUHS [ Rajasthan University of Health Science ].

Previous Year Question Papers of Medicinal Chemistry I

There is a Table of Content given below which help you to find out your required Year Question Paper. You can click on particular year which you want to redirect.
💡 Table of Content

Previous Yr Ques Papers of Medicinal Chemistry I [ 2020 ]

SECTION A 
Ques.1 Attempt the following questions [ 5*2=10 ]
  1. Define Bioisoterism.
  2. Define geometrical isomerism
  3. Discuss the function of Acetylcholine
  4. What is the MOA of Anticonvulsant ?
  5. What are Anesthetics

Ques.2 Attempt the following questions [ 5*2=10 ]
  1. Define Cholinesterase inhibitors.
  2. What are Muscarinic Receptors ?
  3. What are Beta blockers ?
  4. Discuss the MOA of Non-Steroidal anti-inflammatory drugs.
  5. How Naloxone exhibits its effect as narcotic antagonist ?

SECTION B 
Attempt (any two) questions in Long Answer [ 2*10=20 ]
Ques.3 Discuss the classification of Barbiturates and discuss the MOA of Barbiturates. Discuss the SAR of Barbiturates.
Ques.4 What are the SAR of Benzodiazepines. Discuss the Mechanism of Action and uses of Benzodiazepines.
Ques.5 Discuss the factor affecting Drug Metabolism.

SECTION C 
Ques.6 Attempt (any four) question in short answer [ 4*5=20 ]
  1. Discuss reversible and irreversible cholinesterase inhibitor.
  2. Discuss the role of Propranolol as Beta Blocker.
  3. Discuss the role of atropine as cholinergic antagonist also illustrating its effects on body.
  4. Discuss the biosynthesis of Acetylcholine.
  5. Write the synthesis of phenytoin and uses of Phenytoin as Anticonvulsant.

Ques.7 Attempt (any three) question in short answer [ 3*5=15 ]
  1. Discuss the SAR of Morphine Analogues.
  2. Discuss the role of Dopamine as Sympathomimetic Agent.
  3. Discuss the physiochemical parameters : Hydrogen Bonding and Partition Coefficient effect the biological action.
  4. Write the structure of :- (i) Morphine (ii) Codeine (iii) Ibuprofen (iv) Halothane (v) Chlorpromazine


Previous Yr Ques Papers of Medicinal Chemistry I [ 2021 ]

SECTION A 
Ques.1 Attempt the following questions [ 5*2=10 ]
  1. Define Sympathomimetic agents.
  2. Define Isosterism with one example.
  3. Draw the structure and uses of Valproic Acid.
  4. Enumerate Phase II Reaction.
  5. Draw the structure and uses of pethidine (Meperidine).

Ques.2 Attempt the following questions [ 5*2=10 ]
  1. What is Chelation ? Give one example of chelating agent.
  2. Drug Biotransformation.
  3. Give two examples of beta-adrenergic blockers.
  4. Draw the structure and uses of chlorpromazine.
  5. Give two examples of cholinesterase inhibitors.

SECTION B 
Attempt (any two) questions in Long Answer [ 2*10=20 ]
Ques.3 Give a brief account on the classification, structure, mechanism of action and uses of various anticonvulsant.
Ques.4 Define the term sedative and hypnotics. Give a brief account on the classification, mechanism, chemical structure and uses of various sedatives and hypnotics.
Ques.5 Briefly describe the Phase I and Phase II reactions with examples. 

SECTION C 
Ques.6 Attempt (any four) question in short answer [ 4*5=20 ]
  1. Give the synthesis and uses of any one drug : Phenytoin/Salbutamol/Dicyclomine.
  2. Antipsychotics
  3. Give a brief account on SAR, structure and uses of Morphine and its analogues.
  4. Discuss in brief about different physiochemical properties in relation to biological action with suitable example.
  5. Non-Narcotic Analgesics.

Ques.7 Attempt (any three) question in short answer [ 3*5=15 ]
  1. Classify Sympathomimetic/Adrenergic agents. Give the structures and uses of any two direct acting drugs.
  2. Inhalation General Anesthetics.
  3. Classify NSAIDs with examples.
  4. Cholinesterase Inhibitors.

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